Albendazole Bolus 2500mg
Ko te Albendazole he rongoā ārai mate hangai nō te rōpū o ngā benzimidazole e mahi ana ki te whānuitanga o ngā noke, ā, he nui ake te horomanga e mahi ana ki ngā momo noke pakeke o te mate ate.
Te Mahi Rongoā
Ka honoa te Albendazole ki te pūmua microtubule o te kutukutu tuna, ā, ka whai wāhi nui ia. I muri i te whakakotahitanga o te albenzene me te β-tubulin, ka taea te aukati i te whakakotahitanga o te albenzene me te α tubulin ki roto i ngā microtubule. Ko ngā microtubule te hanganga taketake o ngā waeine pūtau maha. He nui ake te kaha o te Albendazole ki ngā nematode tubulin i te kaha o te tubulin mammalian, nō reira he iti te paitini ki ngā mammalian.
Ngā tohu
Te ārai me te rongoā i ngā mate kutukutu i roto i ngā kuao kau me ngā kau pēnei i:
Ngā kutukutu puku:Bunostomum, Cooperia, Chabertia, Haemonchus, Nematodirus, Oesophagostomum, Ostertagia, Strongyloides me Trichostrongylus spp.
Ngā kutukutu pūkahukahu:Dictyocaulus viviparus me D. filaria.
Ngā noke rīpene:Ngā momo Monieza
Mate ate:Fasciola hepatica pakeke.
He pānga whakamate hua anō tō Albendazole.
Ngā ārai-tohu
Te whakahaere i roto i ngā rā 45 tuatahi o te hapūtanga.
Ngā Pānga Taha
Ngā tauhohenga tairongo nui.
Inenga
Mō te whakahaere ā-waha.
Mō ngā kutukutu porowhita, ngā kutukutu rīpene:
Kau / kau nui / hōiho / hipi / koati: 5mg/kg taumaha tinana
Kurī / ngeru: 10 ki te 25mg/kg taumaha tinana
Mō ngā piupiu:
Kau/Pīkau: 10mg/kg taumaha tinana
Hipi/koati: 7.5mg/kg taumaha tinana
Ngā kuao kau me ngā kau: 1 horopeta mō ia 300 kg te taumaha tinana.
Mō te mate ate:
1 horopeta mō ia 250 kg te taumaha tinana.
Whakatūpato
Puritia kia kore e taea e ngā tamariki te toro atu.
Wā Whakamana
3 tau.
Ngā Wā Tangohanga
- Mō te mīti:12 ngā rā.
- Mō te miraka:4 ngā rā.
Rokiroki
Penapena ki te wāhi hauhautanga, maroke hoki, ā, ka tiakina mai i te mārama.
Mō te Whakamahinga Kararehe Anake, Puritia kia kore e taea e ngā tamariki te toro atu
